Acthar is indicated for the treatment of acute exacerbations of multiple sclerosis in adults.

Controlled clinical trials have shown Acthar to be effective in speeding the resolution of acute relapses of multiple sclerosis. However, there is no evidence that it affects the ultimate outcome or natural history of the disease.

Diet and Exercise Tips for Living With MS Relapses

The first step in managing MS relapse symptoms is to take the medications your doctor has prescribed for you. There are also several things you can do that will help enhance your overall sense of well-being.

Before you make any changes to your diet or exercise regimen, it's important to discuss them with your healthcare professional to determine what is best for you.

Watch Your Diet

Eat a wide variety of food:

  • Each day, choose from each of the five basic food groups (grains, vegetables, fruits, dairy, meat and beans)
  • Be sure to include foods high in complex carbs (whole grains, fruit and vegetables)

Cut back on fat and cholesterol:

  • Eat low-fat dairy products
  • Eat lean cuts of meat
  • Limit your meat consumption to 3 or 4 ounces a day
  • Limit the fat you add to foods, such as butter, oils, dressings, and spreads

Reduce sugar intake:

  • Drink less canned soda and sweetened beverages
  • Drink more water
  • Replace sugar in recipes with seasonings like vanilla extract, mint, cinnamon, or ginger

Avoid too much sodium:

  • Add less than one-half teaspoon of salt per day to your food
  • Add flavor to recipes with onions, garlic, parsley, celery, basil, or rosemary

Add Moderate Exercise

When you have MS, it's important not to overstress your body. This may cause fatigue. However, there are things you can do that can help with the stiffness and fatigue that MS relapses can cause:

  • Work with a physical therapist to tailor an exercise program that's right for you
  • Think of exercise as more than running, jumping, or similar aerobic activities. Try to make stretching exercises a part of your day
  • Don't overexert yourself as this will raise your core body temperature and may make symptoms worse

Manage Your Day

Save your energy:

  • Balance periods of activity with periods of rest
  • Plan a daily or weekly schedule of activities and alternate heavy and light tasks
  • Pace yourself; rest before you become exhausted
  • Plan menus before you go to the store and take a shopping list with you
  • Use the same grocery store so you'll know where items are located
  • Set priorities: focus on things that are important and don't feel guilty about not finishing unimportant tasks

Make Your Space MS-Friendly

  • Store frequently used items within easy reach
  • Keep pots and pans near the stove; dishes and glasses should be kept near the sink and eating area
  • Keep heavy items in a permanent place on countertops
  • Use wheeled carts to transport heavy items
  • Use a pail or basket to transport cleaning supplies from room to room
  • Hang items on pegboards for easy access
  • Rearrange your office so that file cabinets, computer, etc are easily accessible

These suggestions are adapted with permission from Managing the Symptoms of Multiple Sclerosis by Randall T. Schapiro, MD.

Acthar is indicated for the treatment of acute exacerbations of multiple sclerosis in adults.

Controlled clinical trials have shown Acthar to be effective in speeding the resolution of acute relapses of multiple sclerosis. However, there is no evidence that it affects the ultimate outcome or natural history of the disease.

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Learn About Home Injection Training Services

Find out how to request free home injection training by licensed nurses.

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Learn About Home Injection Training Services

Find out how to request free home injection training by licensed nurses.

Learn More

Find Acthar Events in Your Community

See what Acthar events are happening near you.

See the Schedule

Important Safety Information

Patients, parents, and caregivers should be aware of the important information about H.P. Acthar® Gel.

Acthar should never be given intravenously (into a vein). Acthar should not be used in patients with a skin condition called scleroderma, bone density loss (osteoporosis), infection throughout the body, eye infection called ocular herpes simplex, recent surgery, history of or a current stomach ulcer, heart problems, high blood pressure, or allergy to pig-derived proteins. Tell your doctor about any health problems or medicines.

Acthar may cause side effects similar to side effects that happen due to treatment with steroid medicines. Not all of these side effects have occurred with Acthar, but they may occur. Acthar is a medicine that affects a patient’s immune system, and therefore patients may be more likely to get new infections, or inactive infections may become active. Acthar has effects on the adrenal gland. When a patient is taking Acthar, their adrenal gland may produce too much of a hormone called cortisol. This can cause symptoms of Cushing’s syndrome (upper body fat, rounded face, thin skin), which is more common in patients who take this medicine for a long time. When a patient stops taking Acthar after a long time, the body may not produce enough cortisol on its own (adrenal insufficiency). The doctor may prescribe a steroid medicine to protect the body until the adrenal gland recovers. Do not stop administering Acthar without talking to your doctor first. Your doctor may check your blood pressure during treatment and may instruct you to make some dietary changes. Patients should not receive certain vaccines during treatment with Acthar. Talk to your doctor about which vaccines are safe for use. Acthar may hide (or mask) symptoms of other conditions or diseases, and it may be more difficult for your doctor to diagnose other conditions or diseases in you or your child during treatment. The person receiving Acthar has an increased risk for bleeding from the stomach or having a stomach ulcer. Inform your doctor about any pain in the stomach area, bloody vomit, or bloody or black stools. While on Acthar, changes in mood and behavior such as irritability, depression, or trouble sleeping may occur.

Other side effects are possible. Acthar may make certain other medical conditions worse such as diabetes (may increase blood sugar); cause eye problems such as cataracts, increased pressure in the eye (glaucoma), and possible damage to the optic nerve; and cause allergic reactions to Acthar (seen as skin rash, swelling of the face, tongue, lips, or throat, and trouble breathing). Acthar may affect growth and physical development after long-term use. Long-term use of Acthar may cause an increase in the size of the heart, but this condition usually goes away after Acthar is stopped.

The most common side effects of Acthar in infants include infections, increased blood pressure, irritability and changes in behavior, changes in appetite and weight, diarrhea, and vomiting. Other adverse reactions reported in adults and children over 2 years of age included abdominal bloating, anxiety, asthma, chest discomfort, congestive heart failure, dizziness, shortness of breath, redness of the face, fluid retention, flushing, headache, injection site pain, tiredness, muscle weakness, nervousness, rapid heart rate, and lack of energy. Tell your doctor if there is any side effect that bothers you or your child or that does not go away.

These are not all of the possible side effects of Acthar. For more information, ask your doctor, nurse, or pharmacist, or call 1-800-465-9217. 1-800-465-9217. You may report side effects to the FDA at 1-800-FDA-1088. 1-800-FDA-1088.

For a full list of indications, contraindications, warnings, precautions, and adverse events related to Acthar, please refer to the full Prescribing Information.

Uses

H.P. Acthar® Gel (repository corticotropin injection) is an adrenocorticotropic hormone (ACTH) analogue used for:

  • Monotherapy treatment of infantile spasms in infants and children under 2 years of age.
  • The treatment of acute exacerbations of multiple sclerosis in adults.
  • Inducing a diuresis or a remission of proteinuria in the nephrotic syndrome without uremia of the idiopathic type or that due to lupus erythematosus.
  • The treatment of an exacerbation or as maintenance therapy in selected cases of systemic dermatomyositis (polymyositis).
  • The following: rheumatic disorders; collagen diseases; dermatologic diseases; allergic states; ophthalmic diseases; and respiratory diseases.

Important Safety Information

Patients, parents, and caregivers should be aware of the important information about H.P. Acthar® Gel.

Acthar should never be given intravenously (into a vein). Acthar should not be used in patients with a skin condition called scleroderma, bone density loss (osteoporosis), infection throughout the body, eye infection called ocular herpes simplex, recent surgery, history of or a current stomach ulcer, heart problems, high blood pressure, or allergy to pig-derived proteins. Tell your doctor about any health problems or medicines.

Acthar may cause side effects similar to side effects that happen due to treatment with steroid medicines. Not all of these side effects have occurred with Acthar, but they may occur. Acthar is a medicine that affects a patient's immune system, and therefore patients may be more likely to get new infections, or inactive infections may become active. Acthar has effects on the adrenal gland. When a patient is taking Acthar, their adrenal gland may produce too much of a hormone called cortisol. This can cause symptoms of Cushing's syndrome (upper body fat, rounded face, thin skin), which is more common in patients who take this medicine for a long time. When a patient stops taking Acthar after a long time, the body may not produce enough cortisol on its own (adrenal insufficiency). The doctor may prescribe a steroid medicine to protect the body until the adrenal gland recovers. Do not stop administering Acthar without talking to your doctor first. Your doctor may check your blood pressure during treatment and may instruct you to make some dietary changes. Patients should not receive certain vaccines during treatment with Acthar. Talk to your doctor about which vaccines are safe for use. Acthar may hide (or mask) symptoms of other conditions or diseases, and it may be more difficult for your doctor to diagnose other conditions or diseases in you or your child during treatment. The person receiving Acthar has an increased risk for bleeding from the stomach or having a stomach ulcer. Inform your doctor about any pain in the stomach area, bloody vomit, or bloody or black stools. While on Acthar, changes in mood and behavior such as irritability, depression, or trouble sleeping may occur.

Other side effects are possible. Acthar may make certain other medical conditions worse such as diabetes (may increase blood sugar); cause eye problems such as cataracts, increased pressure in the eye (glaucoma), and possible damage to the optic nerve; and cause allergic reactions to Acthar (seen as skin rash, swelling of the face, tongue, lips, or throat, and trouble breathing). Acthar may affect growth and physical development after long-term use. Long-term use of Acthar may cause an increase in the size of the heart, but this condition usually goes away after Acthar is stopped.

The most common side effects of Acthar in infants include infections, increased blood pressure, irritability and changes in behavior, changes in appetite and weight, diarrhea, and vomiting. Other adverse reactions reported in adults and children over 2 years of age included abdominal bloating, anxiety, asthma, chest discomfort, congestive heart failure, dizziness, shortness of breath, redness of the face, fluid retention, flushing, headache, injection site pain, tiredness, muscle weakness, nervousness, rapid heart rate, and lack of energy. Tell your doctor if there is any side effect that bothers you or your child or that does not go away.

These are not all of the possible side effects of Acthar. For more information, ask your doctor, nurse, or pharmacist, or call 1-800-465-9217. 1-800-465-9217.

For a full list of indications, contraindications, warnings, precautions, and adverse events related to Acthar, please refer to the full Prescribing Information.

Uses

H.P. Acthar® Gel (repository corticotropin injection) is an adrenocorticotropic hormone (ACTH) analogue used for:

  • Monotherapy treatment of infantile spasms in infants and children under 2 years of age.
  • The treatment of acute exacerbations of multiple sclerosis in adults.
  • Inducing a diuresis or a remission of proteinuria in the nephrotic syndrome without uremia of the idiopathic type or that due to lupus erythematosus.
  • The treatment of an exacerbation or as maintenance therapy in selected cases of systemic dermatomyositis (polymyositis).
  • The following: rheumatic disorders; collagen diseases; dermatologic diseases; allergic states; ophthalmic diseases; and respiratory diseases.